People are being urged to remain in their homes as the gunman remains at large and the area has been sealed off by police. A crime scene is said to be on Humboldt Strasse, near the Jewish cemetery and the area has been cordoned off by police. Emergency services remain in place and a helicopter is circling over the city.
More to follow.
Police said on Twitter they were looking for a suspect.
They tweeted: “We have a deployment in Halle. According to preliminary findings, people killed.
“We are conducting urgent searches. Perpetrator on the run. Please stay at home or look for another secure place.”
Police added several shots were fired and the alleged shooter is fleeing in a vehicle.
Newspaper Bild said on its website the shooting took place in front of a synagogue.
Today is Yom Kippur, the holiest day of the year in Judaism.
There was allegedly a second shooting in Wiedersdorf, near Queis in the district Landsberg.
But this has now stopped, according to Bild.